Journal: The Pharmacogenomics Journal
Article Title: Gene expression analysis in RA: towards personalized medicine
doi: 10.1038/tpj.2013.48
Figure Lengend Snippet: Gene expression signatures as a tool for treatment outcome prediction
Article Snippet: , Whole blood , Discovery set 14 RA, validation set 26 RA , Illumina , SAM, hierarchial clustering (treeview), Ingenuity pathway analysis , Responders vs non-responders , Significant differential expression of IFN-type I response genes (IRGs) at 6 months of RTX treatment. Baseline prediction of non-response to RTX with a 3 and 8 IFN type I response gene signature , Raterman et al. .
Techniques: Gene Expression, Software, Comparison, Expressing, Microarray, Biomarker Discovery, Activation Assay, Real-time Polymerase Chain Reaction, Quantitative Proteomics